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Diseases of finfish

Viral diseases—Infectious pancreatic necrosis

CLICK ON IMAGE TO ENLARGE infectious pancreatic necrosis

Infectious pancreatic necrosis in rainbow trout

Source: T Håstein



Signs of disease

Important: animals with disease may show one or more of the signs below, but disease may still be present in the absence of any signs.

Disease signs at the farm level
Disease signs at the tank and pond level
Clinical signs of disease in an infected animal
Gross signs of disease in an infected animal

Disease agent

Infectious pancreatic necrosis (IPN) virus is a birnavirus, many types of which infect marine finfish and shellfish but do not cause disease. The signs above are of the virulent disease in salmonids.

Host range

Fish that are likely to be severely affected by IPNV:
Atlantic salmon* (Salmo salar)
brook trout* (Salvelinus fontinalis)
brown trout* (Salmo trutta)
danio zebrafish* (Danio rerio)
rainbow trout* (Oncorhynchus mykiss)
yellowtail* (Seriola lalandi)

Other species known to be susceptible to variant strains of birnavirus:
amago salmon* (Oncorhynchus rhodurus)
Arctic char* (Salvelinus alpinus)
Atlantic menhadden* (Brevoortia tyrannus)
carangids* (Carangidae)
chinook salmon* (Oncorhynchus tshawytscha)
chum salmon* (Oncorhynchus keta)
cichlids* (Cichlidae)
coho salmon* (Oncorhynchus kisutch)
common scallop* (Pecten maximus)
cutthroat trout* (Salmo clarkii)
cyprinids* (Cyprinidae)
Danube salmon* (Hucho hucho)
drums/croakers* (Sciaenidae)
eels* (Anguilla spp)
grayling* (Thymallus thymallus)
halibut* (Hippoglossus stenolepis)
herrings/sardines* (Clupeidae)
Japanese amberjack* (Seriola quinqueradiata)
lake trout* (Salvelinus namaycush)
lampreys* (Petromyzontyidae)
left-eye flounders* (Bothidae)
loach* (Misgurnus anguillicaudatus)
loaches* (Cobitidae)
masou salmon* (Oncorhynchus masou)
Pacific salmon* (Oncorhynchus spp)
perches* (Percidae)
pikes* (Esocidae)
silversides* (Atherinidae)
sockeye salmon* (Oncorhynchus nerka)
soles* (Soleidae)
Southwest European nase* (Chondrostoma toxostoma)
striped snakehead* (Channa striatus)
suckers* (Cotostomidae)
summer flounder* (Paralichthys dentatus)
turbot* (Psetta maxima)
white seabass* (Moronidae)
whitefish* (Coregonidae)
carp (Cyprinus carpio)
goldfish (Carassius auratus)
redfin perch (Perca fluviatilis)
southern flounder (Paralichthys lethostigma, estuarine)
yellowfin bream (Acanthopagrus australis)

Asymptomatic carriers of related birnaviruses worldwide are:
coalfish (Pollachius virens)
common carp (Cyprinus carpio)
discus fish (Symphysodon discus)
goldfish (Carrasius auratus)
heron (Ardea cinerea)
loach (Cobitidae)
minnow (Phoxinus phoxinus)
noble crayfish (Astacus astacus)
pike (Esox lucius)
river lamprey (Lampetra fluviatalis)
shore crab (Carcinus maenas)
Spanish barbel (Barbus graellsi)
white suckers (Catostomas commersoni)
whitefish (Coregonidae)

* naturally susceptible (other species have been shown to be experimentally susceptible)

Presence in Asia–Pacific

Map showing presence in Asia–Pacific

IPN has been officially reported from Iran, Japan and the Republic of Korea. A related birnavirus has been identified in the marine environment off Tasmania, Australia, and another from New Zealand in diseased turbot and asymptomatic sea-run chinook salmon.


Differential diagnosis

The differential diagnostic table and the list of similar diseases appearing at the bottom of each disease page refer only to the diseases covered by this field guide. Gross signs observed might well be representative of a wider range of diseases not included here. Therefore, these diagnostic aids should not be read as a guide to a definitive diagnosis, but rather as a tool to help identify the listed diseases that most closely account for the gross signs.

Similar diseases

Viral haemorrhagic septicaemia, infectious haematopoietic necrosis

Sample collection

Because of uncertainty in differentiating diseases using only gross signs, and because some aquatic animal disease agents might pose a risk to humans, you should not try to collect samples unless you have been trained. Instead, you should phone your national hotline number and report your observations. If samples have to be collected, the agency taking the call will advise you on what you need to do. Local or district fisheries/veterinary authorities could advise you on sampling.

Emergency disease hotline

For your national emergency disease hotline number, see Whom to contact if you suspect a disease.

Further reading


The currently accepted procedures for a conclusive diagnosis of IPN are summarised at http://www.oie.int/eng/normes/fmanual/A_00025.htm

These hyperlinks were correct and functioning at the time of publication. infectious pancreaticnecrosis infectious pancreatic necrosis infectious pancreaticnecrosis infectious pancreaticnecrosis infectious pancreaticnecrosis

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